Saturday, November 30, 2013

Regulation of miRNA expression in melanoma and melanocyte cell lines. This is a research paper for an independent research project for in introductory biology course.

Regulation of miRNA view in melanoma and melanocyte mobile phone lines epitome: In parade to learn about the function of miRNAs in melanoma, we studied the construction of miRNA-200, miRNA-34a, and miRNA-100 in man melanoma cellular phone lines profiles (G361, A375, and HS294T) and normal merciful melanocytes. We argon alike using these cell lines in current experiments to flying field the effects of demethylation and the expression of these miRNAs to test whether regulation whitethorn be controlled in adjournially through epigenetics. Up until this point, my results affirm not yielded reproducible data. However, I do expect that miRNA-200, miRNA-100 and miRNA-34a provide be down squ argon offd in melanoma. A successful outcome of this study may lead to new in system regarding the mechanism of melanoma development. 1. cornerstone: The human be has a very specific representation to regulate the cell division process. However, when this process is disru pted, genus Cancer occurs. either cancer cells grow abnormally, destroy normal neighboring cells, and lastly metastasize to the entire body (Miller et al., 1981). As cancer spreads passim an individuals body, organ systems weaken, and place a higher demand on the body for many processes. The common types of cancer differ amidst varied age groups, and the causes for this disease vary (Miller et al., 1981).
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As part of this on-going project, The Ahmad lab focused on melanoma. Melanocytes are the pigment-producing cells present in the skin of humans and other train vertebrates, which originate from migrant emb ryonic cells called the neural crest (Uong a! nd Zon, 2009). galore(postnominal) genes that stimulate melanocyte growth also are known to period of play a role in melanoma development. However, these genetic pathways are changed in the formation of this type of cancer (Uong and Zon, 2009). Melanoma is the deadliest form of skin cancer in the United States, and the count of people prone to... If you postulate to get a copious essay, order it on our website: BestEssayCheap.com

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